Preclinical Testing of eSVS Mesh*

The eSVS Mesh has been studied in a variety of preclinical models to confirm that the device performs as expected. These animal trials showed a statistically significant inhibition of the formation of intimal hyperplasia when the eSVS Mesh was used with an SVG in CABG procedures.** Preclinical trials of the eSVS Mesh technology have been presented in peer-reviewed journals including The Journal of Thoracic and Cardiovascular Surgery in February 2008 and the Journal of Vascular Surgery in June 2009.

 

SHEEP MODEL HISTOLOGY AT 180 DAYS

 
Untreated SVG
Mid-grafts cross-sections and histological staining showing intimal proliferation and thrombus formation with luminal reduction. 
SVG with the eSVS Mesh 

Mid-graft sections and histological stain showing normal intimal and fully functioning endothelial layer with no luminal loss.

 

Caution: Investigational Device Limited by Federal (or United States) law to investigational use
This device is commercially available for use in select international markets

 

** Human clinical studies may not be consistent with animal trial results.